VHL Rabbit pAb, Unconjugated
Artikelnummer:
ABB-A0377
- Bilder (2)
| Artikelname: | VHL Rabbit pAb, Unconjugated |
| Artikelnummer: | ABB-A0377 |
| Hersteller Artikelnummer: | A0377 |
| Alternativnummer: | ABB-A0377-100UL,ABB-A0377-20UL,ABB-A0377-500UL,ABB-A0377-1000UL |
| Hersteller: | ABclonal |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, IF, IHC-P, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Konjugation: | Unconjugated |
| Alternative Synonym: | RCA1, VHL1, pVHL, HRCA1, VHL |
| This gene encodes a component of a ubiquitination complex. The encoded protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. In addition to oxygen-related gene expression, this protein plays a role in many other cellular processes including cilia formation, cytokine signaling, regulation of senescence, and formation of the extracellular matrix. Variants of this gene are associated with von Hippel-Lindau syndrome, pheochromocytoma, erythrocytosis, renal cell carcinoma, and cerebellar hemangioblastoma. |
| Application Verdünnung: | WB,1:500 - 1:2000|IHC-P,1:50 - 1:200|IF/ICC,1:50 - 1:200|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Anwendungsbeschreibung: | Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Epigenetics Nuclear Signaling,Cancer,Tumor suppressors,Cell Biology Developmental Biology,Apoptosis,Cell Cycle,Cell cycle inhibitors,Cell differentiation,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Endocrine Metabolism,Immunology Inflammation,Cardiovascular,Angiogenesis |
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