[KD Validated] NF2 Rabbit pAb, Unconjugated
Artikelnummer:
ABB-A0739
- Bilder (2)
| Artikelname: | [KD Validated] NF2 Rabbit pAb, Unconjugated |
| Artikelnummer: | ABB-A0739 |
| Hersteller Artikelnummer: | A0739 |
| Alternativnummer: | ABB-A0739-100UL,ABB-A0739-20UL,ABB-A0739-500UL,ABB-A0739-1000UL |
| Hersteller: | ABclonal |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, IF, IP, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Konjugation: | Unconjugated |
| Alternative Synonym: | ACN, SCH, BANF, merlin-1, F2 |
| This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that link cytoskeletal components with proteins in the cell membrane. The encoded protein is involved in regulation of contact-dependent inhibition of cell proliferation and functions in cell-cell adhesion and transmembrane signaling. The encoded protein has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics, and proteins involved in regulating ion transport. Disruption of this proteins function has been implicated in tumorigenesis and metastasis. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. |
| Application Verdünnung: | WB,1:500 - 1:2000|IF/ICC,1:50 - 1:200|IP,0.5µg-4µg antibody for 200µg-400µg extracts of whole cells|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Anwendungsbeschreibung: | Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Epigenetics Nuclear Signaling,Protein phosphorylation,Cancer,Tumor suppressors,Signal Transduction,Cell Biology Developmental Biology,Cell Adhesion,Neuroscience |
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