PCNA Rabbit mAb, Unconjugated

Artikelnummer: ABB-A12427
Artikelname: PCNA Rabbit mAb, Unconjugated
Artikelnummer: ABB-A12427
Hersteller Artikelnummer: A12427
Alternativnummer: ABB-A12427-20UL,ABB-A12427-100UL,ABB-A12427-500UL,ABB-A12427-1000UL
Hersteller: ABclonal
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, IHC-P, WB
Spezies Reaktivität: Human
Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
Konjugation: Unconjugated
Alternative Synonym: ATLD2, PCNA
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
Klonalität: Monoclonal
Klon-Bezeichnung: [ARC51324]
Molekulargewicht: 29kDa
NCBI: 5111
UniProt: P12004
Reinheit: Affinity purification
Sequenz: CAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKIEDEEGS
Target-Kategorie: PCNA
Antibody Type: Primary Antibody
Application Verdünnung: WB,1:5000 - 1:20000|IHC-P,1:2000 - 1:10000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse,Rat,African green monkey, ResearchArea: Epigenetics Nuclear Signaling,Cancer,Tumor biomarkers,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology Developmental Biology,Cell Cycle,Stem Cells.