CD74 Rabbit pAb, Unconjugated, Polyclonal

Artikelnummer: ABB-A24487
Artikelname: CD74 Rabbit pAb, Unconjugated, Polyclonal
Artikelnummer: ABB-A24487
Hersteller Artikelnummer: A24487
Alternativnummer: ABB-A24487-20UL,ABB-A24487-100UL,ABB-A24487-1000UL,ABB-A24487-500UL
Hersteller: ABclonal
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, WB
Spezies Reaktivität: Mouse
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Konjugation: Unconjugated
Alternative Synonym: Ii, CLIP, DHLAG, HLADG, Ia-GAMMA, CD74
Enables MHC class II protein binding activity, cytokine receptor activity, and nitric-oxide synthase binding activity. Contributes to cytokine binding activity. Involved in several processes, including macrophage migration inhibitory factor signaling pathway, positive regulation of macromolecule metabolic process, and regulation of signal transduction. Acts upstream of or within several processes, including antigen processing and presentation of exogenous peptide antigen via MHC class II, regulation of T cell differentiation, and thymic T cell selection. Located in several cellular components, including Golgi apparatus, external side of plasma membrane, and multivesicular body. Part of MHC class II protein complex, NOS2-CD74 complex, and macrophage migration inhibitory factor receptor complex. Is expressed in lower jaw, lower jaw incisor, lower jaw molar, and thymus primordium. Orthologous to human CD74 (CD74 molecule).
Klonalität: Polyclonal
Molekulargewicht: 24kDa
NCBI: 16149
UniProt: P04441
Reinheit: Affinity purification
Sequenz: QQQGRLDKLTITSQNLQLESLRMKLPKSAKPVSQMRMATPLLMRPMSMDNMLLGPVKNVTKYGNMTQDHVMHLLTRSGPLEYPQLKGTFPENLKHLKNSMDGVNWKIFESWMKQWLLFEMSKNSLEEKKPTEAPPKEPLDMEDLSSGLGVTRQELGQVTL
Target-Kategorie: Cd74
Antibody Type: Primary Antibody
Application Verdünnung: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Anwendungsbeschreibung: Cross-Reactivity: Mouse. Shipping: Ice Bag
Western blot analysis of lysates from Mouse thymus, using CD74 Rabbit pAb (A24487) at 1:900 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 30s.