PE-CF594 Rabbit anti-Human Bcl-6 mAb, PE/CF594, Monoclonal

Produktübersicht

• Artikelname: PE-CF594 Rabbit anti-Human Bcl-6 mAb, PE/CF594, Monoclonal
• Artikelnummer: ABB-A27730
• Hersteller Artikelnummer: A27730
• Alternativnummer: ABB-A27730-5X100T,ABB-A27730-2X100T,ABB-A27730-100T
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC
• Spezies Reaktivität: Human
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Konjugation: PE/CF594
• Alternative Synonym: BCL5, LAZ3, BCL6A, ZNF51, ZBTB27

Produktbeschreibung

The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

Produkteigenschaften

• Klonalität: Monoclonal
• Konzentration: FC (intra)
• Molekulargewicht: 79kDa
• NCBI: 604
• UniProt: P41182
• Reinheit: Affinity purification
• Target-Kategorie: BCL6

Anwendungsbeschreibung

• Application Verdünnung: FC (intra),5 µl per 10 6 cells in 100 µl volume
• Anwendungsbeschreibung: Cross-Reactivity: Human. ResearchArea: Epigenetics Nuclear Signaling,Transcription Factors,Cancer,Cell Biology Developmental Biology,Apoptosis,Immunology Inflammation,B Cell Receptor Signaling Pathway. Shipping: Ice Bag

Bilder

Flow cytometry: 1X10 6 Daudi cells were intracellularly-stained with PE-CF594 Rabbit IgG isotype control (5 µl/Test,left) or PE-CF594 Rabbit anti-Human BCL6 mAb (A27730,5 µl/Test,right).