APC Rabbit anti-Mouse CD21/CD35 mAb, Monoclonal

Artikelnummer: ABB-A27964
Artikelname: APC Rabbit anti-Mouse CD21/CD35 mAb, Monoclonal
Artikelnummer: ABB-A27964
Hersteller Artikelnummer: A27964
Alternativnummer: ABB-A27964-100UG,ABB-A27964-25UG
Hersteller: ABclonal
Wirt: Rabbit
Kategorie: Antikörper
Applikation: FC
Spezies Reaktivität: Mouse
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Konjugation: APC
Alternative Synonym: Cr1, C3DR, CD21, CD35, Cr-1, Cr-2
Enables complement receptor activity. Acts upstream of or within with a negative effect on complement activation, alternative pathway. Acts upstream of or within several processes, including cellular response to lipopolysaccharide, immunoglobulin mediated immune response, and skeletal system development. Located in external side of plasma membrane. Is expressed in several structures, including brain, hemolymphoid system, liver, placenta, and yolk sac. Human ortholog(s) of this gene implicated in common variable immunodeficiency 7, nasopharynx carcinoma, and systemic lupus erythematosus. Orthologous to human CR2 (complement C3d receptor 2).
Klonalität: Monoclonal
Konzentration: FC
Molekulargewicht: 113kDa
NCBI: 12902
UniProt: P19070
Reinheit: Affinity purification
Sequenz: KNARKPYYSLPIVPGTVLRYTCSPSYRLIGEKAIFCISENQVHATWDKAPPICESVNKTISCSDPIVPGGFMNKGSKAPFRHGDSVTFTCKANFTMKGSKTVWCQANEMWGPTALPVCESDFPLECPSLPTIHNGHHTGQHVDQFVAGLSVTYSCEPGYLLTGKKTIKCLSSGDWDGVIPTCKEAQCEHPGKFPNGQVKEPLSLQVGTTVYFSCNEGYQLQGQPSSQCVIVEQKAIWTKKPVCKEILCPPPPPV
Target-Kategorie: CD21
Application Verdünnung: FC, 0.25 µg per million cells in 100 µl volume
Anwendungsbeschreibung: Cross-Reactivity: Mouse. ResearchArea: Immunology Adaptive Immunity B Cells CDImmunology Adaptive Immunity T Cells CDCardiovascular Blood Blood Cell Antigens RBC Antigens Blood Group AntigensImmunology Innate Immunity Myeloid CellsMicrobiology Protein Human Protein Receptor. Shipping: Ice Bag
Flow cytometry: 1X10 6 C57BL/6 mouse splenocytes were surface-stained with ABflo 450 Rat anti-Mouse CD45R/B220 mAb (A27783,5 µl/Test) and APC Rabbit IgG isotype control (A24173,5 µl/Test,left) or APC Rabbit anti-Mouse CD21/CD35 mAb (A27964,0.25 µg,right).