APC Rabbit anti-Mouse CD21/CD35 mAb, Monoclonal

Product Overview

• Article Name: APC Rabbit anti-Mouse CD21/CD35 mAb, Monoclonal
• Biozol Catalog Number: ABB-A27964
• Supplier Catalog Number: A27964
• Alternative Catalog Number: ABB-A27964-100UG,ABB-A27964-25UG
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: FC
• Species Reactivity: Mouse
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Conjugation: APC
• Alternative Names: Cr1, C3DR, CD21, CD35, Cr-1, Cr-2

Product Description

Enables complement receptor activity. Acts upstream of or within with a negative effect on complement activation, alternative pathway. Acts upstream of or within several processes, including cellular response to lipopolysaccharide, immunoglobulin mediated immune response, and skeletal system development. Located in external side of plasma membrane. Is expressed in several structures, including brain, hemolymphoid system, liver, placenta, and yolk sac. Human ortholog(s) of this gene implicated in common variable immunodeficiency 7, nasopharynx carcinoma, and systemic lupus erythematosus. Orthologous to human CR2 (complement C3d receptor 2).

Product Properties

• Clonality: Monoclonal
• Concentration: FC
• Molecular Weight: 113kDa
• NCBI: 12902
• UniProt: P19070
• Purity: Affinity purification
• Sequence: KNARKPYYSLPIVPGTVLRYTCSPSYRLIGEKAIFCISENQVHATWDKAPPICESVNKTISCSDPIVPGGFMNKGSKAPFRHGDSVTFTCKANFTMKGSKTVWCQANEMWGPTALPVCESDFPLECPSLPTIHNGHHTGQHVDQFVAGLSVTYSCEPGYLLTGKKTIKCLSSGDWDGVIPTCKEAQCEHPGKFPNGQVKEPLSLQVGTTVYFSCNEGYQLQGQPSSQCVIVEQKAIWTKKPVCKEILCPPPPPV
• Target: CD21

Application Notes

• Application Dilute: FC, 0.25 µg per million cells in 100 µl volume
• Application Notes: Cross-Reactivity: Mouse. ResearchArea: Immunology Adaptive Immunity B Cells CDImmunology Adaptive Immunity T Cells CDCardiovascular Blood Blood Cell Antigens RBC Antigens Blood Group AntigensImmunology Innate Immunity Myeloid CellsMicrobiology Protein Human Protein Receptor. Shipping: Ice Bag

Images

Flow cytometry: 1X10 6 C57BL/6 mouse splenocytes were surface-stained with ABflo 450 Rat anti-Mouse CD45R/B220 mAb (A27783,5 µl/Test) and APC Rabbit IgG isotype control (A24173,5 µl/Test,left) or APC Rabbit anti-Mouse CD21/CD35 mAb (A27964,0.25 µg,right).