PE Rabbit anti-Human CD134/OX40 mAb, Monoclonal

Produktübersicht

• Artikelname: PE Rabbit anti-Human CD134/OX40 mAb, Monoclonal
• Artikelnummer: ABB-A28036
• Hersteller Artikelnummer: A28036
• Alternativnummer: ABB-A28036-2X100T,ABB-A28036-100T,ABB-A28036-5X100T
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC
• Spezies Reaktivität: Human
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Konjugation: PE
• Alternative Synonym: OX40, ACT35, CD134, IMD16, TXGP1L

Produktbeschreibung

CD134, also known as OX40 and TNFRSF4, is a 50 kDa type I transmembrane glycoprotein. It is a member of the tumor necrosis factor receptor superfamily (TNFRSF). OX40 is expressed on activated T lymphocytes, including Th1, Th2, Th17, and Treg cell subsets. The interaction between OX40 and its ligand OX40L (TNFSF4) induces B cell proliferation and antibody secretion, and modulates primary T cell expansion and T cell survival. Furthermore, OX40 influences the size of the T cell memory pool and modulates CD4+ T cell tolerance.

Produkteigenschaften

• Klonalität: Monoclonal
• Konzentration: FC
• Molekulargewicht: 29kDa
• NCBI: 7293
• UniProt: P43489
• Reinheit: Affinity purification
• Target-Kategorie: TNFRSF4

Anwendungsbeschreibung

• Application Verdünnung: FC,5 µl per 10 6 cells in 100 µl volume
• Anwendungsbeschreibung: Cross-Reactivity: Human. ResearchArea: Immunology Inflammation,CDs,Cytokines,NF-kB Signaling Pathway. Shipping: Ice Bag

Bilder

Flowcytometry:1X10 6Human PBMC (untreated,left)andHuman PBMC (treated with 10 µg/ml PHA for 2days,right) weresurface-stainedwithPE Rabbit anti-Human CD134/OX40 mAb(A28036,5 µl/test). Cells in the lymphocyte gate were used for analysis.