PE Rabbit anti-Human CD134/OX40 mAb, Monoclonal

Product Overview

• Article Name: PE Rabbit anti-Human CD134/OX40 mAb, Monoclonal
• Biozol Catalog Number: ABB-A28036
• Supplier Catalog Number: A28036
• Alternative Catalog Number: ABB-A28036-2X100T,ABB-A28036-100T,ABB-A28036-5X100T
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: FC
• Species Reactivity: Human
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Conjugation: PE
• Alternative Names: OX40, ACT35, CD134, IMD16, TXGP1L

Product Description

CD134, also known as OX40 and TNFRSF4, is a 50 kDa type I transmembrane glycoprotein. It is a member of the tumor necrosis factor receptor superfamily (TNFRSF). OX40 is expressed on activated T lymphocytes, including Th1, Th2, Th17, and Treg cell subsets. The interaction between OX40 and its ligand OX40L (TNFSF4) induces B cell proliferation and antibody secretion, and modulates primary T cell expansion and T cell survival. Furthermore, OX40 influences the size of the T cell memory pool and modulates CD4+ T cell tolerance.

Product Properties

• Clonality: Monoclonal
• Concentration: FC
• Molecular Weight: 29kDa
• NCBI: 7293
• UniProt: P43489
• Purity: Affinity purification
• Target: TNFRSF4

Application Notes

• Application Dilute: FC,5 µl per 10 6 cells in 100 µl volume
• Application Notes: Cross-Reactivity: Human. ResearchArea: Immunology Inflammation,CDs,Cytokines,NF-kB Signaling Pathway. Shipping: Ice Bag

Images

Flowcytometry:1X10 6Human PBMC (untreated,left)andHuman PBMC (treated with 10 µg/ml PHA for 2days,right) weresurface-stainedwithPE Rabbit anti-Human CD134/OX40 mAb(A28036,5 µl/test). Cells in the lymphocyte gate were used for analysis.