PDE3A Rabbit pAb, Unconjugated, Polyclonal

Produktübersicht

• Artikelname: PDE3A Rabbit pAb, Unconjugated, Polyclonal
• Artikelnummer: ABB-A28279
• Hersteller Artikelnummer: A28279
• Alternativnummer: ABB-A28279-100UL,ABB-A28279-500UL,ABB-A28279-20UL,ABB-A28279-1000UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IP, WB
• Spezies Reaktivität: Mouse
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: HTNB, CGI-PDE, CGI-PDE A, CGI-PDE-A

Produktbeschreibung

This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: 125 kDa
• NCBI: 54611
• UniProt: Q9Z0X4
• Reinheit: Affinity purification
• Target-Kategorie: PDE3A

Anwendungsbeschreibung

• Application Verdünnung: WB,1:1000 - 1:2000|IP,0.5µg-4µg antibody for 200µg-400µg extracts of whole cells|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Mouse. ResearchArea: Signal Transduction. Shipping: Ice Bag

Bilder

Western blot analysis of lysates from Mouse lung using PDE3A Rabbit pAb (A28279) at 1:1000 dilution incubated overnight at 4°C.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25 µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 45 s.