PDE3A Rabbit pAb, Unconjugated, Polyclonal

Product Overview

• Article Name: PDE3A Rabbit pAb, Unconjugated, Polyclonal
• Biozol Catalog Number: ABB-A28279
• Supplier Catalog Number: A28279
• Alternative Catalog Number: ABB-A28279-100UL,ABB-A28279-500UL,ABB-A28279-20UL,ABB-A28279-1000UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IP, WB
• Species Reactivity: Mouse
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: HTNB, CGI-PDE, CGI-PDE A, CGI-PDE-A

Product Description

This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Product Properties

• Clonality: Polyclonal
• Molecular Weight: 125 kDa
• NCBI: 54611
• UniProt: Q9Z0X4
• Purity: Affinity purification
• Target: PDE3A

Application Notes

• Application Dilute: WB,1:1000 - 1:2000|IP,0.5µg-4µg antibody for 200µg-400µg extracts of whole cells|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Mouse. ResearchArea: Signal Transduction. Shipping: Ice Bag

Images

Western blot analysis of lysates from Mouse lung using PDE3A Rabbit pAb (A28279) at 1:1000 dilution incubated overnight at 4°C.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25 µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 45 s.