ABflo 700 Rabbit anti-Human IFN-gamma mAb, Monoclonal

Artikelnummer: ABB-A28423
Artikelname: ABflo 700 Rabbit anti-Human IFN-gamma mAb, Monoclonal
Artikelnummer: ABB-A28423
Hersteller Artikelnummer: A28423
Alternativnummer: ABB-A28423-100T,ABB-A28423-2X100T,ABB-A28423-5X100T
Hersteller: ABclonal
Wirt: Rabbit
Kategorie: Antikörper
Applikation: FC
Spezies Reaktivität: Human
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Konjugation: ABflo 700
Alternative Synonym: IFG, IFI, IMD69
This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases.
Klonalität: Monoclonal
Konzentration: FC (intra)
Molekulargewicht: 19 kDa
NCBI: 3458
UniProt: P01579
Reinheit: Affinity purification
Target-Kategorie: IFNG
Application Verdünnung: FC (intra),5 µl per 10 6 cells in 100 µl volume
Anwendungsbeschreibung: Cross-Reactivity: Human. ResearchArea: Cancer,Tumor immunology,Cell Biology Developmental Biology,Apoptosis,Immunology Inflammation,Cytokines,Cell Intrinsic Innate Immunity Signaling Pathway,Stem Cells. Shipping: Ice Bag
Flow cytometry:1X10 6 Human PBMC (treated with 50 ng/ml PMA and 1 µg/ml Ionomycin for 6 hours and 2µM Monensin for last 5 hours) were intracellularly-stained with ABflo 450 Rabbit anti-Human cCD3 mAb (A27836,5 µl/Test) and ABflo700 Rabbit IgG isotype control (A25976,5 µl/Test,left) or ABflo 700 Rabbit anti-Human IFN-gamma (A28423,5 µl/Test,right).