Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Conjugation:
ABflo 700
Alternative Names:
IFG, IFI, IMD69
This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases.
Flow cytometry:1X10 6 Human PBMC (treated with 50 ng/ml PMA and 1 µg/ml Ionomycin for 6 hours and 2µM Monensin for last 5 hours) were intracellularly-stained with ABflo 450 Rabbit anti-Human cCD3 mAb (A27836,5 µl/Test) and ABflo700 Rabbit IgG isotype control (A25976,5 µl/Test,left) or ABflo 700 Rabbit anti-Human IFN-gamma (A28423,5 µl/Test,right).
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