Prolyl hydroxylase PHD1 (EGLN2) Rabbit mAb, Unconjugated, Monoclonal

Produktübersicht

• Artikelname: Prolyl hydroxylase PHD1 (EGLN2) Rabbit mAb, Unconjugated, Monoclonal
• Artikelnummer: ABB-A3730
• Hersteller Artikelnummer: A3730
• Alternativnummer: ABB-A3730-100UL,ABB-A3730-20UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: EIT6, PHD1, EIT-6, HPH-1, HPH-3, HIFPH1, HIF-PH1, Prolyl hydroxylase PHD1 (EGLN2)

Produktbeschreibung

The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene.

Produkteigenschaften

• Klonalität: Monoclonal
• Molekulargewicht: 44kDa
• NCBI: 112398
• UniProt: Q96KS0
• Reinheit: Affinity purification
• Target-Kategorie: EGLN2

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Epigenetics Nuclear Signaling,Cancer,Invasion and Metastasis,Endocrine Metabolism,Cardiovascular,Hypoxia. Shipping: Ice Bag

Bilder

Western blot analysis of various lysates using Prolyl hydroxylase PHD1 (EGLN2) Rabbit mAb (A3730) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 3min.