EDG1/HEXIM1 Rabbit mAb, Unconjugated, Monoclonal

Produktübersicht

• Artikelname: EDG1/HEXIM1 Rabbit mAb, Unconjugated, Monoclonal
• Artikelnummer: ABB-A3997
• Hersteller Artikelnummer: A3997
• Alternativnummer: ABB-A3997-20UL,ABB-A3997-100UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: EDG1, S1P1, CD363, ECGF1, EDG-1, CHEDG1, D1S3362, EDG1/HEXIM1

Produktbeschreibung

The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants.

Produkteigenschaften

• Klonalität: Monoclonal
• Molekulargewicht: 43kDa
• NCBI: 1901
• UniProt: P21453
• Reinheit: Affinity purification
• Target-Kategorie: S1PR1

Anwendungsbeschreibung

• Application Verdünnung: WB,1:1000 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Signal Transduction,G protein signaling,G-Protein-Coupled ReceptorsGPCR,Cell Biology Developmental Biology,Apoptosis,Cell Adhesion,Cytoskeleton,Immunology Inflammation,CDs,Cardiovascular,Angiogenesis. Shipping: Ice Bag

Bilder

Western blot analysis of various lysates using EDG1/HEXIM1 Rabbit mAb (A3997) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 90s.