EDG1/HEXIM1 Rabbit mAb, Unconjugated, Monoclonal

Product Overview

• Article Name: EDG1/HEXIM1 Rabbit mAb, Unconjugated, Monoclonal
• Biozol Catalog Number: ABB-A3997
• Supplier Catalog Number: A3997
• Alternative Catalog Number: ABB-A3997-20UL,ABB-A3997-100UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: EDG1, S1P1, CD363, ECGF1, EDG-1, CHEDG1, D1S3362, EDG1/HEXIM1

Product Description

The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants.

Product Properties

• Clonality: Monoclonal
• Molecular Weight: 43kDa
• NCBI: 1901
• UniProt: P21453
• Purity: Affinity purification
• Target: S1PR1

Application Notes

• Application Dilute: WB,1:1000 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Signal Transduction,G protein signaling,G-Protein-Coupled ReceptorsGPCR,Cell Biology Developmental Biology,Apoptosis,Cell Adhesion,Cytoskeleton,Immunology Inflammation,CDs,Cardiovascular,Angiogenesis. Shipping: Ice Bag

Images

Western blot analysis of various lysates using EDG1/HEXIM1 Rabbit mAb (A3997) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 90s.