XRCC1 Rabbit mAb, Unconjugated, Monoclonal

Produktübersicht

• Artikelname: XRCC1 Rabbit mAb, Unconjugated, Monoclonal
• Artikelnummer: ABB-A4135
• Hersteller Artikelnummer: A4135
• Alternativnummer: ABB-A4135-20UL,ABB-A4135-100UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: RCC, SCAR26, XRCC1

Produktbeschreibung

The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Produkteigenschaften

• Klonalität: Monoclonal
• Molekulargewicht: 69kDa
• NCBI: 7515
• UniProt: P18887
• Reinheit: Affinity purification
• Target-Kategorie: XRCC1

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Epigenetics Nuclear Signaling,DNA Damage Repair,Cancer,Endocrine Metabolism,Nucleotide metabolism. Shipping: Ice Bag

Bilder

Western blot analysis of various lysates using XRCC1 Rabbit mAb (A4135) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 5s.