AT1R/AGTR1 Rabbit mAb, Unconjugated, Monoclonal

Produktübersicht

• Artikelname: AT1R/AGTR1 Rabbit mAb, Unconjugated, Monoclonal
• Artikelnummer: ABB-A4140
• Hersteller Artikelnummer: A4140
• Alternativnummer: ABB-A4140-100UL,ABB-A4140-20UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: AT1, AG2S, AT1B, AT1R, ATR1, AT1AR, AT1BR, AT2R1, HAT1R, AGTR1B, AT1R/AGTR1

Produktbeschreibung

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed, however, it is now believed that there is only one type 1 receptor gene in humans. Alternative splicing of this gene results in multiple transcript variants.

Produkteigenschaften

• Klonalität: Monoclonal
• Molekulargewicht: 41kDa
• NCBI: 185
• UniProt: P30556
• Reinheit: Affinity purification
• Target-Kategorie: AGTR1

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human. ResearchArea: Cancer,Invasion and Metastasis,Signal Transduction,G protein signaling,G-Protein-Coupled ReceptorsGPCR,Cell Biology Developmental Biology,Growth factors,Endocrine Metabolism,Cardiovascular,Angiogenesis,Blood. Shipping: Ice Bag

Bilder

Western blot analysis of lysates from A-549 cells, using AT1R/AGTR1 Rabbit mAb (A4140) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 180s.