AT1R/AGTR1 Rabbit mAb, Unconjugated, Monoclonal

Product Overview

• Article Name: AT1R/AGTR1 Rabbit mAb, Unconjugated, Monoclonal
• Biozol Catalog Number: ABB-A4140
• Supplier Catalog Number: A4140
• Alternative Catalog Number: ABB-A4140-100UL,ABB-A4140-20UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: AT1, AG2S, AT1B, AT1R, ATR1, AT1AR, AT1BR, AT2R1, HAT1R, AGTR1B, AT1R/AGTR1

Product Description

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed, however, it is now believed that there is only one type 1 receptor gene in humans. Alternative splicing of this gene results in multiple transcript variants.

Product Properties

• Clonality: Monoclonal
• Molecular Weight: 41kDa
• NCBI: 185
• UniProt: P30556
• Purity: Affinity purification
• Target: AGTR1

Application Notes

• Application Dilute: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human. ResearchArea: Cancer,Invasion and Metastasis,Signal Transduction,G protein signaling,G-Protein-Coupled ReceptorsGPCR,Cell Biology Developmental Biology,Growth factors,Endocrine Metabolism,Cardiovascular,Angiogenesis,Blood. Shipping: Ice Bag

Images

Western blot analysis of lysates from A-549 cells, using AT1R/AGTR1 Rabbit mAb (A4140) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 180s.