PGC1 beta Rabbit mAb, Unconjugated, Monoclonal

Produktübersicht

• Artikelname: PGC1 beta Rabbit mAb, Unconjugated, Monoclonal
• Artikelnummer: ABB-A4331
• Hersteller Artikelnummer: A4331
• Alternativnummer: ABB-A4331-100UL,ABB-A4331-20UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: PERC, ERRL1, PGC1B, PGC-1(beta), PGC1 beta

Produktbeschreibung

The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.

Produkteigenschaften

• Klonalität: Monoclonal
• Molekulargewicht: 113kDa
• NCBI: 133522
• UniProt: Q86YN6
• Reinheit: Affinity purification
• Target-Kategorie: PPARGC1B

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human,Rat. ResearchArea: Epigenetics Nuclear Signaling,Nuclear Receptor Signaling,Endocrine Metabolism,Mitochondrial metabolism,Mitochondrial markers,Endocrine and metabolic diseases,Diabetes,Cardiovascular,Lipids,Fatty Acids. Shipping: Ice Bag

Bilder

Western blot analysis of various lysates using PGC1 beta Rabbit mAb (A4331) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 10s.