PGC1 beta Rabbit mAb, Unconjugated, Monoclonal

Product Overview

• Article Name: PGC1 beta Rabbit mAb, Unconjugated, Monoclonal
• Biozol Catalog Number: ABB-A4331
• Supplier Catalog Number: A4331
• Alternative Catalog Number: ABB-A4331-100UL,ABB-A4331-20UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: PERC, ERRL1, PGC1B, PGC-1(beta), PGC1 beta

Product Description

The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.

Product Properties

• Clonality: Monoclonal
• Molecular Weight: 113kDa
• NCBI: 133522
• UniProt: Q86YN6
• Purity: Affinity purification
• Target: PPARGC1B

Application Notes

• Application Dilute: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human,Rat. ResearchArea: Epigenetics Nuclear Signaling,Nuclear Receptor Signaling,Endocrine Metabolism,Mitochondrial metabolism,Mitochondrial markers,Endocrine and metabolic diseases,Diabetes,Cardiovascular,Lipids,Fatty Acids. Shipping: Ice Bag

Images

Western blot analysis of various lysates using PGC1 beta Rabbit mAb (A4331) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 10s.