Galactosidase alpha (GLA) Rabbit mAb, Unconjugated, Monoclonal

Produktübersicht

• Artikelname: Galactosidase alpha (GLA) Rabbit mAb, Unconjugated, Monoclonal
• Artikelnummer: ABB-A5119
• Hersteller Artikelnummer: A5119
• Alternativnummer: ABB-A5119-20UL,ABB-A5119-100UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: GALA, Galactosidase alpha (GLA)

Produktbeschreibung

This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.

Produkteigenschaften

• Klonalität: Monoclonal
• Molekulargewicht: 49kDa
• NCBI: 2717
• UniProt: P06280
• Reinheit: Affinity purification
• Target-Kategorie: GLA

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Cardiovascular,Blood. Shipping: Ice Bag

Bilder

Western blot analysis of various lysates using Galactosidase alpha (GLA) (GLA) Rabbit mAb (A5119) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 3min.