Galactosidase alpha (GLA) Rabbit mAb, Unconjugated, Monoclonal

Product Overview

• Article Name: Galactosidase alpha (GLA) Rabbit mAb, Unconjugated, Monoclonal
• Biozol Catalog Number: ABB-A5119
• Supplier Catalog Number: A5119
• Alternative Catalog Number: ABB-A5119-20UL,ABB-A5119-100UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: GALA, Galactosidase alpha (GLA)

Product Description

This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.

Product Properties

• Clonality: Monoclonal
• Molecular Weight: 49kDa
• NCBI: 2717
• UniProt: P06280
• Purity: Affinity purification
• Target: GLA

Application Notes

• Application Dilute: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Cardiovascular,Blood. Shipping: Ice Bag

Images

Western blot analysis of various lysates using Galactosidase alpha (GLA) (GLA) Rabbit mAb (A5119) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 3min.