NPHP3 Rabbit pAb, Unconjugated

Produktübersicht

• Artikelname: NPHP3 Rabbit pAb, Unconjugated
• Artikelnummer: ABB-A8580
• Hersteller Artikelnummer: A8580
• Alternativnummer: ABB-A8580-100UL, ABB-A8580-20UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: MKS7, NPH3, RHPD, RHPD1, SLSN3, CFAP31, NPHP3

Produktbeschreibung

This gene encodes a protein containing a coiled-coil (CC) domain, a tubulin-tyrosine ligase (TTL) domain, and a tetratrico peptide repeat (TPR) domain. The encoded protein interacts with nephrocystin, it is required for normal ciliary development, and it functions in renal tubular development. Mutations in this gene are associated with nephronophthisis type 3, and also with renal-hepatic-pancreatic dysplasia, and Meckel syndrome type 7. Naturally occurring read-through transcripts exist between this gene and the downstream ACAD11 (acyl-CoA dehydrogenase family, member 11) gene.

Produkteigenschaften

• Molekulargewicht: 151kDa
• NCBI: 27031
• UniProt: Q7Z494
• Reinheit: Affinity purification
• Target-Kategorie: NPHP3

Anwendungsbeschreibung

• Application Verdünnung: WB,1:200 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse

Bilder

Western blot analysis of various lysates using NPHP3 Rabbit pAb (A8580) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 30s.