NPHP3 Rabbit pAb, Unconjugated

Product Overview

• Article Name: NPHP3 Rabbit pAb, Unconjugated
• Biozol Catalog Number: ABB-A8580
• Supplier Catalog Number: A8580
• Alternative Catalog Number: ABB-A8580-100UL, ABB-A8580-20UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: MKS7, NPH3, RHPD, RHPD1, SLSN3, CFAP31, NPHP3

Product Description

This gene encodes a protein containing a coiled-coil (CC) domain, a tubulin-tyrosine ligase (TTL) domain, and a tetratrico peptide repeat (TPR) domain. The encoded protein interacts with nephrocystin, it is required for normal ciliary development, and it functions in renal tubular development. Mutations in this gene are associated with nephronophthisis type 3, and also with renal-hepatic-pancreatic dysplasia, and Meckel syndrome type 7. Naturally occurring read-through transcripts exist between this gene and the downstream ACAD11 (acyl-CoA dehydrogenase family, member 11) gene.

Product Properties

• Molecular Weight: 151kDa
• NCBI: 27031
• UniProt: Q7Z494
• Purity: Affinity purification
• Target: NPHP3

Application Notes

• Application Dilute: WB,1:200 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human,Mouse

Images

Western blot analysis of various lysates using NPHP3 Rabbit pAb (A8580) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 30s.