Complement factor H Rabbit mAb, Unconjugated

Produktübersicht

• Artikelname: Complement factor H Rabbit mAb, Unconjugated
• Artikelnummer: ABB-A8798
• Hersteller Artikelnummer: A8798
• Alternativnummer: ABB-A8798-100UL, ABB-A8798-20UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: FH, HF, HF1, HF2, HUS, FHL1, AHUS1, AMBP1, ARMD4, ARMS1, CFHL3, Complement factor H

Produktbeschreibung

This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Produkteigenschaften

• Molekulargewicht: 139kDa
• NCBI: 3075
• UniProt: P08603
• Reinheit: Affinity purification
• Target-Kategorie: CFH

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human, ResearchArea: Immunology Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway.

Bilder

Western blot analysis of lysates from BxPC-3 cells, using Complement factor H Rabbit mAb (A8798) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 60s.