Complement factor H Rabbit mAb, Unconjugated

Product Overview

• Article Name: Complement factor H Rabbit mAb, Unconjugated
• Biozol Catalog Number: ABB-A8798
• Supplier Catalog Number: A8798
• Alternative Catalog Number: ABB-A8798-100UL, ABB-A8798-20UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: FH, HF, HF1, HF2, HUS, FHL1, AHUS1, AMBP1, ARMD4, ARMS1, CFHL3, Complement factor H

Product Description

This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Product Properties

• Molecular Weight: 139kDa
• NCBI: 3075
• UniProt: P08603
• Purity: Affinity purification
• Target: CFH

Application Notes

• Application Dilute: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human, ResearchArea: Immunology Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway.

Images

Western blot analysis of lysates from BxPC-3 cells, using Complement factor H Rabbit mAb (A8798) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 60s.