alpha 1 Spectrin Rabbit mAb, Unconjugated

Produktübersicht

• Artikelname: alpha 1 Spectrin Rabbit mAb, Unconjugated
• Artikelnummer: ABB-A9597
• Hersteller Artikelnummer: A9597
• Alternativnummer: ABB-A9597-100UL, ABB-A9597-20UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: EL2, HPP, HS3, SPH3, SPTA, alpha 1 Spectrin

Produktbeschreibung

This gene encodes a member of a family of molecular scaffold proteins that link the plasma membrane to the actin cytoskeleton and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms a component of the erythrocyte plasma membrane. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis-2, pyropoikilocytosis, and spherocytosis, type 3.

Produkteigenschaften

• Molekulargewicht: 280kDa
• NCBI: 6708
• UniProt: P02549
• Reinheit: Affinity purification
• Target-Kategorie: SPTA1

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse,Rat, ResearchArea: Signal Transduction,Cell Biology Developmental Biology,Cytoskeleton,Microfilaments,Cardiovascular,Blood.

Bilder

Western blot analysis of various lysates using alpha 1 Spectrin Rabbit mAb (A9597) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 10s.