alpha 1 Spectrin Rabbit mAb, Unconjugated

Product Overview

• Article Name: alpha 1 Spectrin Rabbit mAb, Unconjugated
• Biozol Catalog Number: ABB-A9597
• Supplier Catalog Number: A9597
• Alternative Catalog Number: ABB-A9597-100UL, ABB-A9597-20UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: EL2, HPP, HS3, SPH3, SPTA, alpha 1 Spectrin

Product Description

This gene encodes a member of a family of molecular scaffold proteins that link the plasma membrane to the actin cytoskeleton and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms a component of the erythrocyte plasma membrane. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis-2, pyropoikilocytosis, and spherocytosis, type 3.

Product Properties

• Molecular Weight: 280kDa
• NCBI: 6708
• UniProt: P02549
• Purity: Affinity purification
• Target: SPTA1

Application Notes

• Application Dilute: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human,Mouse,Rat, ResearchArea: Signal Transduction,Cell Biology Developmental Biology,Cytoskeleton,Microfilaments,Cardiovascular,Blood.

Images

Western blot analysis of various lysates using alpha 1 Spectrin Rabbit mAb (A9597) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 10s.