Phospho-MAX-S11 Rabbit pAb, Unconjugated

Produktübersicht

• Artikelname: Phospho-MAX-S11 Rabbit pAb, Unconjugated
• Artikelnummer: ABB-AP0072
• Hersteller Artikelnummer: AP0072
• Alternativnummer: ABB-AP0072-1000UL,ABB-AP0072-100UL,ABB-AP0072-20UL,ABB-AP0072-500UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: bHLHd4, Phospho-MAX-S11

Produktbeschreibung

The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: 18kDa
• NCBI: 4149
• UniProt: P61244
• Reinheit: Affinity purification
• Sequenz: VESDE
• Target-Kategorie: MAX
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human, ResearchArea: Epigenetics Nuclear Signaling,Transcription Factors,Protein phosphorylation,Cancer,Tumor suppressors,Signal Transduction.

Bilder

Western blot analysis of lysates from Jurkat cells, using Phospho-MAX-S11 Rabbit pAb (AP0072) at 1:1000 dilution. Jurkat cells were treated with serum-starvation overnight.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% BSA.