Phospho-MAX-S11 Rabbit pAb, Unconjugated

Product Overview

• Article Name: Phospho-MAX-S11 Rabbit pAb, Unconjugated
• Biozol Catalog Number: ABB-AP0072
• Supplier Catalog Number: AP0072
• Alternative Catalog Number: ABB-AP0072-1000UL,ABB-AP0072-100UL,ABB-AP0072-20UL,ABB-AP0072-500UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: bHLHd4, Phospho-MAX-S11

Product Description

The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.

Product Properties

• Clonality: Polyclonal
• Molecular Weight: 18kDa
• NCBI: 4149
• UniProt: P61244
• Purity: Affinity purification
• Sequence: VESDE
• Target: MAX
• Antibody Type: Primary Antibody

Application Notes

• Application Dilute: WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human, ResearchArea: Epigenetics Nuclear Signaling,Transcription Factors,Protein phosphorylation,Cancer,Tumor suppressors,Signal Transduction.

Images

Western blot analysis of lysates from Jurkat cells, using Phospho-MAX-S11 Rabbit pAb (AP0072) at 1:1000 dilution. Jurkat cells were treated with serum-starvation overnight.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% BSA.