Phospho-SP1-T739 Rabbit pAb, Unconjugated

Artikelnummer: ABB-AP0231
Artikelname: Phospho-SP1-T739 Rabbit pAb, Unconjugated
Artikelnummer: ABB-AP0231
Hersteller Artikelnummer: AP0231
Alternativnummer: ABB-AP0231-100UL, ABB-AP0231-20UL
Hersteller: ABclonal
Wirt: Rabbit
Kategorie: Antikörper
Spezies Reaktivität: Human
Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
Konjugation: Unconjugated
Alternative Synonym: SP1, Phospho-SP1-T739
The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.
Konzentration: WB
Molekulargewicht: 81kDa
NCBI: 6667
UniProt: P08047
Reinheit: Affinity purification
Target-Kategorie: SP1
Application Verdünnung: WB,1:500 - 1:2000
Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse,Rat, ResearchArea: Epigenetics Nuclear Signaling,Transcription Factors,Endocrine Metabolism,Mitochondrial metabolism,Nucleotide metabolism,Neuroscience,Neurodegenerative Diseases,Stem Cells.
Western blot analysis of lysates from 3T3 cells, using Phospho-SP1-T739 Rabbit pAb (AP0231).
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% BSA.