Phospho-SP1-T739 Rabbit pAb, Unconjugated

Product Overview

• Article Name: Phospho-SP1-T739 Rabbit pAb, Unconjugated
• Biozol Catalog Number: ABB-AP0231
• Supplier Catalog Number: AP0231
• Alternative Catalog Number: ABB-AP0231-100UL, ABB-AP0231-20UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: SP1, Phospho-SP1-T739

Product Description

The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.

Product Properties

• Concentration: WB
• Molecular Weight: 81kDa
• NCBI: 6667
• UniProt: P08047
• Purity: Affinity purification
• Target: SP1

Application Notes

• Application Dilute: WB,1:500 - 1:2000
• Application Notes: Cross-Reactivity: Human,Mouse,Rat, ResearchArea: Epigenetics Nuclear Signaling,Transcription Factors,Endocrine Metabolism,Mitochondrial metabolism,Nucleotide metabolism,Neuroscience,Neurodegenerative Diseases,Stem Cells.

Images

Western blot analysis of lysates from 3T3 cells, using Phospho-SP1-T739 Rabbit pAb (AP0231).
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% BSA.