Phospho-DOK2-Y299 Rabbit pAb, Unconjugated

Produktübersicht

• Artikelname: Phospho-DOK2-Y299 Rabbit pAb, Unconjugated
• Artikelnummer: ABB-AP0250
• Hersteller Artikelnummer: AP0250
• Alternativnummer: ABB-AP0250-100UL, ABB-AP0250-20UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: p56DOK, p56dok-2, Phospho-DOK2-Y299

Produktbeschreibung

The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.

Produkteigenschaften

• Molekulargewicht: 45kDa
• NCBI: 9046
• UniProt: O60496
• Reinheit: Affinity purification
• Target-Kategorie: DOK2

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:2000|IF/ICC,1:100 - 1:200
• Anwendungsbeschreibung: Cross-Reactivity: Human, ResearchArea: Cancer,Signal Transduction,Kinase,Tyrosine kinases,ErbB-HER Signaling Pathway.

Bilder

Western blot analysis of lysates from Jurkat cells using Phospho-DOK2-Y299 Rabbit pAb (AP0250).
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% BSA.