Phospho-DOK2-Y299 Rabbit pAb, Unconjugated

Product Overview

• Article Name: Phospho-DOK2-Y299 Rabbit pAb, Unconjugated
• Biozol Catalog Number: ABB-AP0250
• Supplier Catalog Number: AP0250
• Alternative Catalog Number: ABB-AP0250-100UL, ABB-AP0250-20UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: IF, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: p56DOK, p56dok-2, Phospho-DOK2-Y299

Product Description

The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.

Product Properties

• Molecular Weight: 45kDa
• NCBI: 9046
• UniProt: O60496
• Purity: Affinity purification
• Target: DOK2

Application Notes

• Application Dilute: WB,1:500 - 1:2000|IF/ICC,1:100 - 1:200
• Application Notes: Cross-Reactivity: Human, ResearchArea: Cancer,Signal Transduction,Kinase,Tyrosine kinases,ErbB-HER Signaling Pathway.

Images

Western blot analysis of lysates from Jurkat cells using Phospho-DOK2-Y299 Rabbit pAb (AP0250).
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% BSA.