Phospho-PRMT4/CARM1-S228 Rabbit pAb, Unconjugated

Produktübersicht

• Artikelname: Phospho-PRMT4/CARM1-S228 Rabbit pAb, Unconjugated
• Artikelnummer: ABB-AP0319
• Hersteller Artikelnummer: AP0319
• Alternativnummer: ABB-AP0319-20UL,ABB-AP0319-1000UL,ABB-AP0319-100UL,ABB-AP0319-500UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: PRMT4, Phospho-PRMT4/CARM1-S228

Produktbeschreibung

This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts specifically on histones and other chromatin-associated proteins and is involved in regulation of gene expression. The enzyme may act in association with other proteins or within multi-protein complexes and may play a role in cell type-specific functions and cell lineage specification. A related pseudogene is located on chromosome 9.

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: 66kDa
• NCBI: 10498
• UniProt: Q86X55
• Reinheit: Affinity purification
• Sequenz: VKSNN
• Target-Kategorie: CARM1
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human, ResearchArea: Epigenetics Nuclear Signaling,Epigenetic writers and erasers of core Histones,Nuclear Receptor Signaling,Nuclear hormone receptors,Cancer,Tumor suppressors,p53 pathway,Signal Transduction,Cell Biology Developmental Biology,Cell Cycle,Cell cycle inhibitors,Endocrine Metabolism,Lipid Metabolism.

Bilder

Western blot analysis of lysates from Jurkat cells, using Phospho-PRMT4/CARM1-S228 Rabbit pAb (AP0319) at 1:1000 dilution. Jurkat cells were treated with Calyculin A (100 nM) at 37°C for 30 minutes.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 10s.