Synthetic peptide. This information is considered to be commercially sensitive.
Konjugation:
Unconjugated
Alternative Synonym:
MACS, 80K-L, PKCSL, PRKCSL, Phospho-MARCKS-S158
The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
Cross-Reactivity: Human,Mouse,Rat, ResearchArea: Signal Transduction,Kinase,Cell Biology Developmental Biology,Cytoskeleton,Endocrine Metabolism,Neuroscience,Calcium Signaling,Cardiovascular.
Western blot analysis of lysates from 3T3 cells using Phospho-MARCKS-S158 Rabbit pAb (AP0402). Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% BSA.
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