Phospho-MARCKS-S158 Rabbit pAb, Unconjugated

Product Overview

• Article Name: Phospho-MARCKS-S158 Rabbit pAb, Unconjugated
• Biozol Catalog Number: ABB-AP0402
• Supplier Catalog Number: AP0402
• Alternative Catalog Number: ABB-AP0402-100UL, ABB-AP0402-20UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: MACS, 80K-L, PKCSL, PRKCSL, Phospho-MARCKS-S158

Product Description

The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.

Product Properties

• Concentration: WB
• Molecular Weight: 32kDa
• NCBI: 4082
• UniProt: P29966
• Purity: Affinity purification
• Target: MARCKS

Application Notes

• Application Dilute: WB,1:500 - 1:2000
• Application Notes: Cross-Reactivity: Human,Mouse,Rat, ResearchArea: Signal Transduction,Kinase,Cell Biology Developmental Biology,Cytoskeleton,Endocrine Metabolism,Neuroscience,Calcium Signaling,Cardiovascular.

Images

Western blot analysis of lysates from 3T3 cells using Phospho-MARCKS-S158 Rabbit pAb (AP0402).
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% BSA.