Phospho-alpha-Synuclein-S129 Rabbit pAb, Unconjugated

Produktübersicht

• Artikelname: Phospho-alpha-Synuclein-S129 Rabbit pAb, Unconjugated
• Artikelnummer: ABB-AP0450
• Hersteller Artikelnummer: AP0450
• Alternativnummer: ABB-AP0450-500UL,ABB-AP0450-20UL,ABB-AP0450-1000UL,ABB-AP0450-100UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: PD1, NACP, PARK1, PARK4, Phospho-alpha-Synuclein-S129

Produktbeschreibung

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimers disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: 14kDa
• NCBI: 6622
• UniProt: P37840
• Reinheit: Affinity purification
• Sequenz: MPSEE
• Target-Kategorie: SNCA
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse,Rat, ResearchArea: Protein phosphorylation,Cell Biology Developmental Biology,Apoptosis,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimers Disease,Dopamine Signaling in Parkinsons Disease,Neurodegenerative Diseases Markers.

Bilder

Western blot analysis of lysates from mouse brain tissue, using Phospho-alpha-Synuclein-S129 Rabbit pAb (AP0450).
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% BSA.