Phospho-NDRG1-T346 Rabbit pAb, Unconjugated

Produktübersicht

• Artikelname: Phospho-NDRG1-T346 Rabbit pAb, Unconjugated
• Artikelnummer: ABB-AP0792
• Hersteller Artikelnummer: AP0792
• Alternativnummer: ABB-AP0792-100UL,ABB-AP0792-20UL,ABB-AP0792-500UL,ABB-AP0792-1000UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: GC4, RTP, DRG1, NDR1, NMSL, TDD5, CAP43, CMT4D, DRG-1, HMSNL, RIT42, TARG1, PROXY1, Phospho-NDRG1-T346

Produktbeschreibung

This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: 43kDa
• NCBI: 10397
• UniProt: Q92597
• Reinheit: Affinity purification
• Sequenz: SHTSE
• Target-Kategorie: NDRG1
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse,Rat, ResearchArea: Epigenetics Nuclear Signaling,Protein phosphorylation,Cancer,Invasion and Metastasis,Signal Transduction,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Angiogenesis.

Bilder

Western blot analysis of lysates from C6 cells, using Phospho-NDRG1-T346 Rabbit pAb (AP0792) at 1:1000 dilution. C6 cells were treated with IGF-1 (50 ng/ml) at 37°C for 30 minutes after serum-starvation overnight.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 180s.