Phospho-NDRG1-T346 Rabbit pAb, Unconjugated

Product Overview

• Article Name: Phospho-NDRG1-T346 Rabbit pAb, Unconjugated
• Biozol Catalog Number: ABB-AP0792
• Supplier Catalog Number: AP0792
• Alternative Catalog Number: ABB-AP0792-100UL,ABB-AP0792-20UL,ABB-AP0792-500UL,ABB-AP0792-1000UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: GC4, RTP, DRG1, NDR1, NMSL, TDD5, CAP43, CMT4D, DRG-1, HMSNL, RIT42, TARG1, PROXY1, Phospho-NDRG1-T346

Product Description

This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Product Properties

• Clonality: Polyclonal
• Molecular Weight: 43kDa
• NCBI: 10397
• UniProt: Q92597
• Purity: Affinity purification
• Sequence: SHTSE
• Target: NDRG1
• Antibody Type: Primary Antibody

Application Notes

• Application Dilute: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human,Mouse,Rat, ResearchArea: Epigenetics Nuclear Signaling,Protein phosphorylation,Cancer,Invasion and Metastasis,Signal Transduction,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Angiogenesis.

Images

Western blot analysis of lysates from C6 cells, using Phospho-NDRG1-T346 Rabbit pAb (AP0792) at 1:1000 dilution. C6 cells were treated with IGF-1 (50 ng/ml) at 37°C for 30 minutes after serum-starvation overnight.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 180s.