Phospho-Ezrin-Y353 Rabbit pAb
Artikelnummer:
ABB-AP1118
- Bilder (1)
| Artikelname: | Phospho-Ezrin-Y353 Rabbit pAb |
| Artikelnummer: | ABB-AP1118 |
| Hersteller Artikelnummer: | AP1118 |
| Alternativnummer: | ABB-AP1118-100UL, ABB-AP1118-20UL |
| Hersteller: | ABclonal |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Alternative Synonym: | CVL, CVIL, VIL2, HEL-S-105, Phospho-Ezrin-Y353 |
| The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. |
| Application Verdünnung: | WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Anwendungsbeschreibung: | Cross-Reactivity: Human, ResearchArea: Epigenetics Nuclear Signaling,RNA Binding,Protein phosphorylation,Cancer,Signal Transduction,Cell Biology Developmental Biology,Cytoskeleton,Microfilaments,Immunology Inflammation,B Cell Receptor Signaling Pathway. |
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Western blot analysis of lysates from 293T cells, using Phospho-Ezrin-Y353 Rabbit pAb (A0703). 293T cells were treated with ATP(5 mM) at 30°C for 1 hour. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% BSA. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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