Human Interleukin 18 Binding Protein (IL18BP) ELISA Kit, Biotin
Artikelnummer:
ABB-RK01662
Hersteller Artikelnummer:
RK01662
Alternativnummer:
ABB-RK01662-96T
Hersteller:
ABclonal
Kategorie:
Kits/Assays
Spezies Reaktivität:
Human
Immunogen:
Serum, plasma, cell culture supernatant, and other biological fluids.
Konjugation:
Biotin
Alternative Synonym:
FVH, IL18BPa, IL18BP
The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohns disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
