Human Interleukin 18 Binding Protein (IL18BP) ELISA Kit, Biotin
Biozol Catalog Number:
ABB-RK01662
Supplier Catalog Number:
RK01662
Alternative Catalog Number:
ABB-RK01662-96T
Manufacturer:
ABclonal
Category:
Kits/Assays
Species Reactivity:
Human
Immunogen:
Serum, plasma, cell culture supernatant, and other biological fluids.
Conjugation:
Biotin
Alternative Names:
FVH, IL18BPa, IL18BP
The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohns disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
