Recombinant Human IL-17A&IL-17F Protein

Artikelnummer: ABB-RP02627
Artikelname: Recombinant Human IL-17A&IL-17F Protein
Artikelnummer: ABB-RP02627
Hersteller Artikelnummer: RP02627
Alternativnummer: ABB-RP02627-100UG
Hersteller: ABclonal
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Immunogen: Gly24-Ala155(IL-17A)&Arg31-Gln163(IL-17F)
Alternative Synonym: IL-17A,Interleukin-17A,CTLA-8,IL-17,IL-17F,IL24,ML-1,Interleukin-17F
Interleukin?17A (IL?17A), also known as CTLA?8, is a 15?20 kDa glycosylated cytokine that plays an important role in anti?microbial and chronic inflammation. The six IL?17 cytokines (IL?17A?F) are encoded by separate genes but adopt a conserved cystine knot fold .IL-17A is a ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC . Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines.
Konzentration: < 1 EU/µg of the protein by LAL method.
Molekulargewicht: 15.1 kDa (IL-17A), 15.7 kDa (IL-17F)
NCBI: 3605
UniProt: Q16552
Reinheit: 95 % as determined by Tris-Bis PAGE, 95 % as determined by HPLC.
Target-Kategorie: IL-17A&amp;F
Anwendungsbeschreibung: Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles. ResearchArea: Other Recombinant Protein