Recombinant Mouse Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein, Human

Produktübersicht

• Artikelname: Recombinant Mouse Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein, Human
• Artikelnummer: ABB-RP02655
• Hersteller Artikelnummer: RP02655
• Alternativnummer: ABB-RP02655-100UG
• Hersteller: ABclonal
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Mouse
• Immunogen: Phe31-Val988(ITGAV) acidic tail&Gly22-Asn706(ITGB6) basic tail
• Alternative Synonym: ITGAV&ITGB6,Integrin alpha V beta 6

Produktbeschreibung

ITGAV&ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion . ITGAV&ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 .

Produkteigenschaften

• Konzentration: < 1 EU/µg of the protein by LAL method.
• Molekulargewicht: 111.6 kDa (ITGAV) &amp; 79.2 kDa (ITGB6)
• NCBI: 16410
• UniProt: P43406
• Reinheit: 95 % as determined by Tris-Bis PAGE, 95 % as determined by HPLC.
• Sequenz: FNLDVESPAEYAGPEGSYFGFAVDFFEPSTSSRMFLLVGAPKANTTQPGIVEGGQVLKCECSSSRRCQPIEFDSTGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSKNIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIISKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIEDFVSGVPRAARTLGMVYI
• Target-Kategorie: Integrin alpha V beta 6 (ITGAV&amp;ITGB6) Heterodimer

Anwendungsbeschreibung

• Anwendungsbeschreibung: Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles. ResearchArea: Other Recombinant Protein