Recombinant Mouse Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein, Human

Produktübersicht

• Artikelname: Recombinant Mouse Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein, Human
• Artikelnummer: ABB-RP02656
• Hersteller Artikelnummer: RP02656
• Alternativnummer: ABB-RP02656-100UG
• Hersteller: ABclonal
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Mouse
• Immunogen: Phe31-Val988(ITGAV) acidic tail&Gly22-Ser679(ITGB8) basic tail
• Alternative Synonym: Integrin alpha V beta 8,ITGAV&ITGB8

Produktbeschreibung

Deletions of the genes encoding the integrin alphaVbeta8 (Itgav, Itgb8) have been shown to result in abnormal vascular development in the CNS, including prenatal and perinatal hemorrhage. Other work has indicated that a major function of this integrin in vivo is to promote TGFbeta activation.

Produkteigenschaften

• Konzentration: < 1 EU/µg of the protein by LAL method.
• Molekulargewicht: 111.6(ITGAV) &amp; 76.6(ITGB8) kDa
• NCBI: 16410
• UniProt: P43406
• Reinheit: 95 % as determined by Tris-Bis PAGE, 95 % as determined by HPLC.
• Sequenz: FNLDVESPAEYAGPEGSYFGFAVDFFEPSTSSRMFLLVGAPKANTTQPGIVEGGQVLKCECSSSRRCQPIEFDSTGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSKNIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIISKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIEDFVSGVPRAARTLGMVYI
• Target-Kategorie: Integrin alpha V beta 8 (ITGAV&amp;ITGB8) Heterodimer

Anwendungsbeschreibung

• Anwendungsbeschreibung: Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles. ResearchArea: Other Recombinant Protein