Recombinant Mouse Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein, Human

Product Overview

• Article Name: Recombinant Mouse Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein, Human
• Biozol Catalog Number: ABB-RP02656
• Supplier Catalog Number: RP02656
• Alternative Catalog Number: ABB-RP02656-100UG
• Manufacturer: ABclonal
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Mouse
• Immunogen: Phe31-Val988(ITGAV) acidic tail&Gly22-Ser679(ITGB8) basic tail
• Alternative Names: Integrin alpha V beta 8,ITGAV&ITGB8

Product Description

Deletions of the genes encoding the integrin alphaVbeta8 (Itgav, Itgb8) have been shown to result in abnormal vascular development in the CNS, including prenatal and perinatal hemorrhage. Other work has indicated that a major function of this integrin in vivo is to promote TGFbeta activation.

Product Properties

• Concentration: < 1 EU/µg of the protein by LAL method.
• Molecular Weight: 111.6(ITGAV) &amp; 76.6(ITGB8) kDa
• NCBI: 16410
• UniProt: P43406
• Purity: 95 % as determined by Tris-Bis PAGE, 95 % as determined by HPLC.
• Sequence: FNLDVESPAEYAGPEGSYFGFAVDFFEPSTSSRMFLLVGAPKANTTQPGIVEGGQVLKCECSSSRRCQPIEFDSTGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSKNIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIISKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIEDFVSGVPRAARTLGMVYI
• Target: Integrin alpha V beta 8 (ITGAV&amp;ITGB8) Heterodimer

Application Notes

• Application Notes: Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles. ResearchArea: Other Recombinant Protein