Recombinant Mouse TNFRSF18/GITR/CD357 Protein, Human

Produktübersicht

• Artikelname: Recombinant Mouse TNFRSF18/GITR/CD357 Protein, Human
• Artikelnummer: ABB-RP02678
• Hersteller Artikelnummer: RP02678
• Alternativnummer: ABB-RP02678-100UG
• Hersteller: ABclonal
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Mouse
• Immunogen: Ser22-His153
• Alternative Synonym: CD357, GITR, GITR-D, TNFRSF18, AITR

Produktbeschreibung

GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.

Produkteigenschaften

• Konzentration: < 1 EU/µg of the protein by LAL method.
• Molekulargewicht: 15.2 kDa
• NCBI: 21936
• UniProt: Q8C4K3
• Reinheit: 95 % as determined by Tris-Bis PAGE, 95 % as determined by HPLC.
• Target-Kategorie: GITR/TNFRSF18

Anwendungsbeschreibung

• Anwendungsbeschreibung: Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles. ResearchArea: Other Recombinant Protein