Recombinant Mouse TNFRSF18/GITR/CD357 Protein, Human

Catalog Number: ABB-RP02678
Article Name: Recombinant Mouse TNFRSF18/GITR/CD357 Protein, Human
Biozol Catalog Number: ABB-RP02678
Supplier Catalog Number: RP02678
Alternative Catalog Number: ABB-RP02678-100UG
Manufacturer: ABclonal
Host: Human
Category: Proteine/Peptide
Species Reactivity: Mouse
Immunogen: Ser22-His153
Alternative Names: CD357, GITR, GITR-D, TNFRSF18, AITR
GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Concentration: < 1 EU/µg of the protein by LAL method.
Molecular Weight: 15.2 kDa
NCBI: 21936
UniProt: Q8C4K3
Purity: 95 % as determined by Tris-Bis PAGE, 95 % as determined by HPLC.
Target: GITR/TNFRSF18
Application Notes: Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles. ResearchArea: Other Recombinant Protein